{"version":"1.0","provider_name":"\u0645\u0624\u0633\u0633\u0629 \u0627\u0644\u0641\u0644\u0643 \u0627\u0644\u062e\u064a\u0631\u064a\u0629","provider_url":"https:\/\/alfolk.net\/en\/","title":"Is there a radical treatment for Down syndrome? (Part 2) - \u0645\u0624\u0633\u0633\u0629 \u0627\u0644\u0641\u0644\u0643 \u0627\u0644\u062e\u064a\u0631\u064a\u0629","type":"rich","width":600,"height":338,"html":"<blockquote class=\"wp-embedded-content\" data-secret=\"tkuXY4Errw\"><a href=\"https:\/\/alfolk.net\/en\/is-there-a-treatment-for-down-syndrome\/\">Is there a radical treatment for Down syndrome? (Part 2)<\/a><\/blockquote><iframe sandbox=\"allow-scripts\" security=\"restricted\" src=\"https:\/\/alfolk.net\/en\/is-there-a-treatment-for-down-syndrome\/embed\/#?secret=tkuXY4Errw\" width=\"600\" height=\"338\" title=\"&#8220;Is there a radical treatment for Down syndrome? (Part 2)&#8221; &#8212; \u0645\u0624\u0633\u0633\u0629 \u0627\u0644\u0641\u0644\u0643 \u0627\u0644\u062e\u064a\u0631\u064a\u0629\" data-secret=\"tkuXY4Errw\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\" class=\"wp-embedded-content\"><\/iframe><script type=\"text\/javascript\">\n\/*! This file is auto-generated *\/\n!function(c,d){\"use strict\";var e=!1,o=!1;if(d.querySelector)if(c.addEventListener)e=!0;if(c.wp=c.wp||{},c.wp.receiveEmbedMessage);else if(c.wp.receiveEmbedMessage=function(e){var t=e.data;if(!t);else if(!(t.secret||t.message||t.value));else if(\/[^a-zA-Z0-9]\/.test(t.secret));else{for(var r,s,a,i=d.querySelectorAll('iframe[data-secret=\"'+t.secret+'\"]'),n=d.querySelectorAll('blockquote[data-secret=\"'+t.secret+'\"]'),o=new RegExp(\"^https?:$\",\"i\"),l=0;l<n.length;l++)n[l].style.display=\"none\";for(l=0;l<i.length;l++)if(r=i[l],e.source!==r.contentWindow);else{if(r.removeAttribute(\"style\"),\"height\"===t.message){if(1e3<(s=parseInt(t.value,10)))s=1e3;else if(~~s<200)s=200;r.height=s}if(\"link\"===t.message)if(s=d.createElement(\"a\"),a=d.createElement(\"a\"),s.href=r.getAttribute(\"src\"),a.href=t.value,!o.test(a.protocol));else if(a.host===s.host)if(d.activeElement===r)c.top.location.href=t.value}}},e)c.addEventListener(\"message\",c.wp.receiveEmbedMessage,!1),d.addEventListener(\"DOMContentLoaded\",t,!1),c.addEventListener(\"load\",t,!1);function t(){if(o);else{o=!0;for(var e,t,r,s=-1!==navigator.appVersion.indexOf(\"MSIE 10\"),a=!!navigator.userAgent.match(\/Trident.*rv:11\\.\/),i=d.querySelectorAll(\"iframe.wp-embedded-content\"),n=0;n<i.length;n++){if(!(r=(t=i[n]).getAttribute(\"data-secret\")))r=Math.random().toString(36).substr(2,10),t.src+=\"#?secret=\"+r,t.setAttribute(\"data-secret\",r);if(s||a)(e=t.cloneNode(!0)).removeAttribute(\"security\"),t.parentNode.replaceChild(e,t);t.contentWindow.postMessage({message:\"ready\",secret:r},\"*\")}}}}(window,document);\n<\/script>\n","thumbnail_url":"https:\/\/alfolk.net\/wp-content\/uploads\/2021\/09\/WhatsApp-Image-2021-09-13-at-2.20.50-PM.jpeg","thumbnail_width":1000,"thumbnail_height":1000,"description":"Scientific dreams of treating Down syndrome Simulation of brain cells from patients with Down syndrome is a promising potential treatment Chromosomes are thread-like parts located inside cells, and carry genetic information, so-called genes. And as it was previously said in previous articles that normal children are born with a distinct and fixed number of them, which is 46 chromosomes (23 pairs), children with Down syndrome have a problem which is the presence of a third copy of chromosome number 21, which negatively affects the development and Child&#8217;s mind and body development. In an attempt to control this syndrome, which affects about 6,000 babies every year in the United States of America, a study conducted by Rutgers University found that targeting the OLIG2 gene on chromosome 21 before birth could help in the future treatment of the syndrome. During the study, whose results were published in the journal Cell Stem Cell, the researchers used stem cells that can turn into brain cells to develop two experimental models: One of them is a three-dimensional model of the brain, and the other is a mouse brain model with human cells implanted inside&nbsp; In order to explore the early brain development associated with Down syndrome, and to monitor the improvement that can be achieved when targeting the \u201cOLIG2\u201d gene. They found that this restores balance to two types of neurons in the brain that are responsible for excitation and inhibition, and it also helps to improve awareness after birth. According to a report published on the Rutgers University website in conjunction with the publication of the study, the researchers obtained skin cells from children with Down syndrome (somatic cells), then genetically reprogrammed them into embryonic stem cells, and then transformed them into cells similar to brain cells during early life and growth. Scientific note: Stem cells can be converted into any type of cell in the human body, but they cannot produce a complete organ. They are also useful tools for drug development and production of laboratory models to understand diseases, which is what the American research team did. &#8220;Using brain cells derived from [&hellip;]"}